Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 17/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768576 | 0.86 | KDM4E (0.42) | PTGER1MAOBKDM4E | |
| SCHEMBL4765586 | 0.84 | PTGER1 (0.74) | PTGER1MAOB | |
| SCHEMBL4923812 | 0.84 | PTGER1 (0.59) | PTGER1 | |
| SCHEMBL4774676 | 0.81 | KMT2A (0.45) | MAOBKDM4E | |
| SCHEMBL14034918 | 0.81 | PTGER1 (0.58) | PTGER1 | |
| SCHEMBL4774734 | 0.76 | PTGER1 (0.67) | PTGER1 | |
| SCHEMBL4724417 | 0.76 | PTGER1 (0.75) | PTGER1 | |
| SCHEMBL2956494 | 0.75 | PTGER1 (0.77) | PTGER1 | |
| SCHEMBL4915825 | 0.75 | PTGER1 (0.60) | PTGER1MAOBKDM4E | |
| SCHEMBL4774737 | 0.75 | PTGER1 (0.80) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | PTGER1, PTGER2, PTGER3 | PTGER1 1/4885MAOB 588/4885KDM4E 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.