⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779567 | 0.75 | — | — | |
| SCHEMBL2887822 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL10777424 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL28848454 | 0.72 | — | — | |
| SCHEMBL4142041 | 0.71 | USP2 (0.35) | — | |
| SCHEMBL776422 | 0.67 | USP2 (0.32) | — | |
| SCHEMBL4136368 | 0.67 | — | — | |
| SCHEMBL778550 | 0.67 | CA1 (0.31) | — | |
| SCHEMBL10935329 | 0.63 | — | — | |
| SCHEMBL2809007 | 0.63 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957053-A | Oxoethylene compound or pharmaceutically acceptable salt thereof, preparation method and application thereof, pharmaceutical composition and application thereof | 中国医学科学院医药生物技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| US-10246662-B2 | Pigmented, Fine-Structured, Tribological Composite Material | LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) | 2019-04-02 | — | — | US | disclosed |
| EP-2794769-B9 | PIGMENTED, FINE-STRUCTURED, TRIBOLOGICAL COMPOSITE MATERIAL | LEIBNIZ INSTITUT FUER NEUE MAT GEMEINNUETZIGE GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| EP-2794769-B1 | PIGMENTED, FINE-STRUCTURED, TRIBOLOGICAL COMPOSITE MATERIAL | LEIBNIZ INST FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) | 2016-09-14 | — | — | EP | disclosed |
| US-9371411-B2 | Abrasion-resistant and alkali-resistant coatings or moulded bodies having a low-energy surface | LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) | 2016-06-21 | — | — | US | disclosed |
| US-20140329729-A1 | Pigmented, Fine-Structured, Tribological Composite Material | LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) | 2014-11-06 | — | — | US | disclosed |
| EP-2794769-A1 | PIGMENTED, FINE-STRUCTURED, TRIBOLOGICAL COMPOSITE MATERIAL | Leibniz-Institut für Neue Materialien gemeinnützige GmbH (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092835-A1 | PIGMENTED, FINE-STRUCTURED, TRIBOLOGICAL COMPOSITE MATERIAL | LEIBNIZ-INSTITUT FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
| US-20080008838-A1 | Abrasion-Resistant and Alkali-Resistant Coatings or Moulded Bodies Having a Low-Energy Surface | LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZ (DE) | 2008-01-10 | — | — | US | disclosed |