Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 14/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923036 | 0.96 | PTGER1 (0.61) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4925217 | 0.94 | PTGER1 (0.59) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4927580 | 0.93 | PTGER1 (0.56) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4914154 | 0.93 | GAA (0.58) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4925046 | 0.91 | SMN1; SMN2 (0.56) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4924566 | 0.91 | SMN1; SMN2 (0.71) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4924893 | 0.91 | GAA (0.55) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4917875 | 0.90 | SMN1; SMN2 (0.55) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4926308 | 0.90 | GAA (0.59) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL4924878 | 0.90 | SMN1; SMN2 (0.55) | PTGER1GAASMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | PTGER1, PTGER2, PTGER3 | PTGER1 1/4885GAA 4729/4885SMN1; SMN2 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.