Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.66 |
| ▸ | ITGA5 | P08648 | 19/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.66 |
| ▸ | ITGAV | P06756 | 5/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14270774 | 0.92 | ITGB1 (0.67) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL4064730 | 0.92 | ITGB1 (0.78) | ITGB1ITGA5ITGB3ITGAVITGA2B | |
| SCHEMBL4929723 | 0.91 | ITGB1 (0.65) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4920461 | 0.89 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL14270716 | 0.89 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4071574 | 0.87 | ITGB1 (0.65) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4074937 | 0.86 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4391450 | 0.85 | ITGB1 (0.78) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL4931464 | 0.84 | ITGB1 (0.66) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL4918910 | 0.84 | ITGB1 (0.81) | ITGB1ITGA5ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045521-A1 | PHENYLALANINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045521-A1 | PHENYLALANINE DERIVATIVES | ITGB5, ITGB1, ITGA2B | ITGB1 2/4885ITGA5 7/4885ITGB3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.