⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31180512 | 1.00 | — | — | |
| SCHEMBL11955164 | 0.76 | AAK1 (0.34) | — | |
| SCHEMBL28459550 | 0.75 | AAK1 (0.40) | — | |
| SCHEMBL802806 | 0.75 | — | — | |
| SCHEMBL30296911 | 0.75 | — | — | |
| SCHEMBL5644419 | 0.75 | — | — | |
| SCHEMBL6347184 | 0.75 | — | — | |
| SCHEMBL541874 | 0.75 | — | — | |
| SCHEMBL170573 | 0.75 | — | — | |
| SCHEMBL31527977 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528784-B2 | Alkynyl-(heteroaryl)-carboxamide HCN1 inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2026-01-20 | — | — | US | disclosed |
| CN-114746408-B | Alkynyl- (heteroaryl) -carboxamide HCN1 inhibitors | 豪夫迈·罗氏有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119325339-A | Comprising difluorobutenamide herbicidal composition of compounds | 石原产业株式会社 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024092115-A2 | MK2 INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023227946-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2023-11-30 | — | — | WO | disclosed |
| CN-117119887-A | Method for improving sugar cane sugar yield | 科迪华农业科技有限责任公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2023220741-A1 | ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF | DICE MOLECULES SV, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023141511-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-112996393-B | Compositions comprising pyridine carboxylic acid herbicides and synthetic auxin herbicides or auxin transport inhibitors | 科迪华农业科技有限责任公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023064585-A1 | 7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | VANDERBILT UNIVERSITY (US) | 2023-04-20 | — | — | WO | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |
| WO-2010038465-A1 | 8-SUBSTITUTED ISOQUINOLINE DERIVATIVE AND USE THEREOF | 旭化成ファーマ株式会社 (JP) | 2010-04-08 | — | — | WO | disclosed |
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| WO-2006035967-A1 | PYRIDINE DERIVATIVES AND THEIR USE AS MEDICAMENTS FOR TREATING DISEASES RELATED TO MCH RECEPTOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |