Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4510825 | 0.87 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL21187595 | 0.87 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL30158189 | 0.82 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL10854921 | 0.80 | NOTUM (0.78) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL6780467 | 0.80 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL25374470 | 0.80 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL30542835 | 0.80 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL20898022 | 0.80 | CA12 (0.45) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL9816066 | 0.80 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4NOTUM | |
| SCHEMBL31170822 | 0.80 | NOTUM (0.78) | GRIA1GRIA2GRIA3GRIA4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305082-A1 | 1,4-Bis-N-Oxide-5,8- Dihydroxyanthracenedione Compounds and the Use Thereof | NOVACEA, INC. | 2008-12-11 | — | — | US | disclosed |
| US-20080305082-A1 | 1,4-Bis-N-Oxide-5,8- Dihydroxyanthracenedione Compounds and the Use Thereof | NOVACEA, INC. | 2008-12-11 | — | — | US | disclosed |
| US-20080305082-A1 | 1,4-Bis-N-Oxide-5,8- Dihydroxyanthracenedione Compounds and the Use Thereof | NOVACEA, INC. | 2008-12-11 | — | — | US | disclosed |
| WO-2008103320-A1 | METHODS OF TREATING OPHTHALMIC DISORDERS WITH ANTHRAQUINONES | NOVACEA, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305082-A1 | 1,4-Bis-N-Oxide-5,8- Dihydroxyanthracenedione Compounds and the Use Thereof | RB1, BRCA1, CCNA1 | GRIA1 2485/4885GRIA2 4020/4885GRIA3 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.