Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492126 | 0.85 | CHRNA7 (0.46) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492099 | 0.85 | CHRNA7 (0.46) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492249 | 0.81 | CHRNA7 (0.50) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492552 | 0.81 | CHRNA7 (0.50) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492950 | 0.80 | CHRNA7 (0.50) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL493048 | 0.80 | CHRNA7 (0.50) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492600 | 0.80 | CHRNA7 (0.47) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492530 | 0.79 | CHRNA7 (0.46) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492859 | 0.79 | CHRNA7 (0.46) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492879 | 0.78 | CHRNA7 (0.47) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106066-B2 | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2012-01-31 | — | — | US | claimed |