Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933371 | 1.00 | HDAC1 (0.50) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4930166 | 0.93 | HDAC1 (0.51) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4930171 | 0.93 | HDAC1 (0.51) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4933463 | 0.90 | HDAC1 (0.57) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4933474 | 0.90 | HDAC1 (0.57) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL8291643 | 0.89 | HDAC1 (0.49) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4922535 | 0.88 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4921882 | 0.88 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4922530 | 0.88 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4921878 | 0.88 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | HDAC1 1/4885HDAC3 2/4885HDAC2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.