Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933732 | 1.00 | POLB (0.51) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4934047 | 0.99 | POLB (0.52) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4934062 | 0.99 | POLB (0.52) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4937113 | 0.93 | MEN1 (0.48) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4937099 | 0.93 | MEN1 (0.48) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4935906 | 0.90 | TP53 (0.54) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4935918 | 0.90 | TP53 (0.54) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4935049 | 0.88 | TP53 (0.47) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4935065 | 0.88 | TP53 (0.47) | POLBTP53SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4933633 | 0.87 | TP53 (0.47) | POLBTP53SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | KUREHA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1707560-A1 | HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE | Kureha Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | HDAC5, HDAC1, HDAC9 | POLB 633/4885TP53 2597/4885SMN1; SMN2 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.