Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198618 | 0.84 | FOLH1 (0.50) | AKR1C3MAPTHTTALDH1A1HPGD | |
| SCHEMBL3125292 | 0.82 | MEN1 (0.54) | AKR1C3MAPTHTTAKR1C2ALDH1A1 | |
| SCHEMBL170063 | 0.79 | AKR1C3 (0.50) | AKR1C3MAPTCYP19A1GAAALDH1A1 | |
| SCHEMBL943893 | 0.79 | AKR1C3 (0.50) | AKR1C3MAPTCYP19A1GAAALDH1A1 | |
| SCHEMBL30560007 | 0.79 | AKR1C3 (0.50) | AKR1C3MAPTCYP19A1GAAALDH1A1 | |
| SCHEMBL28284541 | 0.79 | HTT (0.44) | AKR1C3MAPTHTTALDH1A1HPGD | |
| Propane SCHEMBL28419357 | 0.79 | ELANE (0.47) | AKR1C3MAPTCYP19A1GAAALDH1A1 | |
| SCHEMBL8331815 | 0.79 | MEN1 (0.41) | AKR1C3MAPTHTTAKR1C2ALDH1A1 | |
| SCHEMBL29881091 | 0.78 | AKR1C3 (0.57) | AKR1C3MAPTCYP19A1GAAALDH1A1 | |
| SCHEMBL723171 | 0.78 | AKR1C3 (0.57) | AKR1C3MAPTCYP19A1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054950-A1 | CANCER TREATMENT USING MTDP INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| EP-3373971-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING CANCER CELLS | Massachusetts Institute of Technology (US) | 2018-09-19 | — | — | EP | disclosed |
| US-20170168056-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING CANCER CELLS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2017-06-15 | — | — | US | disclosed |
| WO-2017083854-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING CANCER CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-05-18 | — | — | WO | disclosed |
| US-20080207952-A1 | NOVEL THERAPEUTIC APPLICATIONS OF NATURAL POLY ISOPRENYLATED BENZOPHENONE DERIVATIVES AS DRUGS/MEDICAMENTS | MAJEED MUHAMMED | 2008-08-28 | — | — | US | disclosed |
| US-6956061-B2 | Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| US-20040082662-A1 | Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082662-A1 | Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof | GGPS1, PGGT1B, GNPAT | AKR1C3 1442/4885MAPT 2407/4885CYP19A1 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.