SCHEMBL4935800

SCHEMBL4935800

O=C1NNC(=O)C1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11242649 0.86
SCHEMBL7115148 0.77 IDUA (0.35)
SCHEMBL133284 0.72 HSD17B10 (0.39)
Water SCHEMBL11883570 0.69 HSD17B10 (0.38)
SCHEMBL2369309 0.61
SCHEMBL18499992 0.61
SCHEMBL17032222 0.61
SCHEMBL667239 0.61
SCHEMBL22733471 0.61 IDUA (0.35)
SCHEMBL17085510 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080287390-A1 Pyrazolidinol compounds A-VIRAL AS (NO) 2008-11-20 US disclosed
US-20070037772-A1 Pyrazolidinol compounds A-VIRAL AS (NO) 2007-02-15 US disclosed
US-20060121449-A1 Method for selection of compounds which inhibit clonal cell growth and use thereof TJOTTA ENOK 2006-06-08 US disclosed
EP-1194409-B1 PYRAZOLIDINOL COMPOUNDS VIRAL ASA A (NO) 2006-02-01 EP disclosed
EP-1549742-A1 METHOD FOR SELECTION OF COMPOUNDS WHICH INHIBIT CLONAL CELL GROWTH AND USE THEREOF Tjötta, Enok (NO) 2005-07-06 EP disclosed
US-6852749-B1 Pyrazolidinol compounds A-VIRAL AS (NO) 2005-02-08 US disclosed
US-20040152751-A1 Pyrazolidinol compounds TJOTTA ENOK (NO) 2004-08-05 US disclosed
WO-2004055175-A1 METHOD FOR SELECTION OF COMPOUNDS WHICH INHIBIT CLONAL CELL GROWTH AND USE THEREOF TJOETTA ENOK (NO) 2004-07-01 WO disclosed
US-20040023987-A1 Sustained release compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-02-05 US disclosed
EP-1291023-A1 SUSTAINED RELEASE COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 2003-03-12 EP disclosed