Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932524 | 0.87 | CNR2 (0.72) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL4650498 | 0.86 | CNR2 (0.70) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL4649634 | 0.86 | CNR2 (0.70) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL4931244 | 0.83 | CNR2 (1.00) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL4648968 | 0.83 | CNR2 (0.58) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL4648729 | 0.81 | CNR2 (0.69) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL4929647 | 0.81 | CNR2 (0.64) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL4926710 | 0.80 | CNR2 (0.93) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5077103 | 0.80 | CNR2 (0.76) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5214859 | 0.78 | CNR2 (0.78) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280952-A1 | Pyridine Derivatives as Connabinoid Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-11-13 | — | — | US | disclosed |
| US-20080280952-A1 | Pyridine Derivatives as Connabinoid Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-11-13 | — | — | US | disclosed |
| US-20080280952-A1 | Pyridine Derivatives as Connabinoid Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280952-A1 | Pyridine Derivatives as Connabinoid Receptor Modulators | CNR1, CNR2, P2RY1 | CNR2 2/4885CYP2D6 1087/4885CYP2C19 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.