Tryptamine

Tryptamine

SCHEMBL4936407

NCCc1c[nH]c2ccccc12.[Au]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 9/20 0.96
HTR2C P28335 4/20 0.96
HTR6 P50406 4/20 0.96
CYP3A4 P08684 3/20 0.96
HTR1D P28221 3/20 0.96
MPO P05164 2/20 0.96
CYP1A2 P05177 2/20 0.96
CYP2D6 P10635 2/20 0.96
HTR1B P28222 2/20 0.96
HTR7 P34969 2/20 0.96
TAAR1 Q96RJ0 2/20 0.96
CYP2A6 P11509 1/20 0.96
NFKB1 P19838 1/20 0.96
CTSK P43235 1/20 0.96
CYP2A13 Q16696 1/20 0.96
PMP22 Q01453 1/20 0.93
MEN1 O00255 1/20 0.62
MAPT P10636 1/20 0.62
AHR P35869 1/20 0.62
KMT2A Q03164 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptamine SCHEMBL8714244 0.98 HTR2A (1.00) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL26725 0.98 HTR2A (1.00) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL29373222 0.98 HTR2A (1.00) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL29771300 0.96 HTR2A (0.96) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL10874156 0.96 HTR2A (0.96) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL28686775 0.96 PMP22 (1.00) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL274183 0.96 PMP22 (1.00) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL22127053 0.96 HTR2A (0.96) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL9472063 0.96 HTR2A (0.96) HTR2AHTR2CHTR6CYP3A4HTR1D
Tryptamine SCHEMBL599675 0.96 HTR2A (0.96) HTR2AHTR2CHTR6CYP3A4HTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080222754-A1 Methods of Modulating Glucosinolate Production in Plants THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-09-11 US disclosed
US-20050223431-A1 Methods of modulating glucosinolate production in plants THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, AN ARIZONA CORPORATION. 2005-10-06 US disclosed