Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4938560

CCN1CCN(C)CC1.N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.39
MC4R P32245 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
PAOX Q6QHF9 1/20 0.37
GAA P10253 1/20 0.37
RAD52 P43351 1/20 0.37
GFER P55789 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
PHGDH O43175 1/20 0.35
MGLL Q99685 1/20 0.35
HTR1A P08908 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2323195 0.97
SCHEMBL14524205 0.97 CHRNA7 (0.41) CHRNA7MC4RALDH1A1KDM4EMAPT
SCHEMBL81189 0.97
SCHEMBL6662807 0.97 CHRNA7 (0.41) CHRNA7MC4RALDH1A1KDM4EMAPT
SCHEMBL17616057 0.97 CHRNA7 (0.41) CHRNA7MC4RALDH1A1KDM4EMAPT
Hydrochloric Acid SCHEMBL28585027 0.94 CHRNA7 (0.39) CHRNA7MC4RALDH1A1KDM4EMAPT
SCHEMBL22957950 0.91 KDM1A (0.41) CHRNA7MC4RALDH1A1KDM4EMAPT
SCHEMBL19020372 0.91 KDM1A (0.41) CHRNA7MC4RALDH1A1KDM4EMAPT
Dimethylamine SCHEMBL603412 0.88 CHRNA7 (0.37) CHRNA7MC4RALDH1A1KDM4EMAPT
SCHEMBL15217803 0.88 CHRNA7 (0.37) CHRNA7MC4RALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080275191-A1 polyamines used as curing agents and as polymerization catalysts or chain extenders in urethane applications AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-11-06 US claimed
US-12188139-B2 Alternating current electrolysis for use in organic synthesis WAYNE STATE UNIVERSITY (US) 2025-01-07 US disclosed
US-20230091947-A1 ALTERNATING CURRENT ELECTROLYSIS FOR USE IN ORGANIC SYNTHESIS WAYNE STATE UNIVERSITY (US) 2023-03-23 US disclosed
US-11499238-B2 Alternating current electrolysis for use in organic synthesis WAYNE STATE UNIVERSITY (US) 2022-11-15 US disclosed
US-20210207274-A1 ALTERNATING CURRENT ELECTROLYSIS FOR USE IN ORGANIC SYNTHESIS WAYNE STATE UNIVERSITY (US) 2021-07-08 US disclosed
EP-2860212-B1 New amine composition EVONIK OPERATIONS GMBH (DE) 2020-02-26 EP disclosed
US-9944836-B2 Amine composition EVONIK DEGUSSA GMBH (DE) 2018-04-17 US disclosed
US-20150368531-A1 Amine Composition AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-12-24 US disclosed
CN-102333779-B Benzopyran and benzoxex PI3K inhibitor compounds and methods of use GENENTECH, INC. (US) 2015-12-09 CN disclosed
US-9133306-B2 Amine composition AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-15 US disclosed
EP-2860212-A1 New amine composition AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-04-15 EP disclosed
EP-1985644-B1 Polyamine composition AIR PROD & CHEM (US) 2015-01-14 EP disclosed
US-20080275191-A1 polyamines used as curing agents and as polymerization catalysts or chain extenders in urethane applications AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-11-06 US disclosed
EP-1985644-A1 Polyamine composition Air Products and Chemicals, Inc. (US) 2008-10-29 EP disclosed
US-5863879-A POLYMER IS FORMED BY REACTING A POLYMER CONTAINING VINYLAMINE UNIT WITH COMPOUNDS CONTAINING ALDEHYDE OR KETO GROUPS AND OPTIONAL OTHER AMINE OR ALOCHOL CONTAINING COMPOUNDS SUCH AS AMINAL, HEMIAMINAL OR AMINAL ACETATE BASF AKTIENGESELLSCHAFT (DE) 1999-01-26 US disclosed
US-4328223-A 2-Amino-3a,4,5,6-tetrahydro-perimidine derivatives and their medicinal use in combatting circulatory diseases BAYER AKTIENGESELLSCHAFT (DE) 1982-05-04 US disclosed
US-4187306-A Benzodiazepine-diones, a process for their production and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1980-02-05 US disclosed