Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540647 | 0.86 | KCNA5 (1.00) | KCNA5 | |
| SCHEMBL4536779 | 0.85 | KCNA5 (0.69) | KCNA5 | |
| SCHEMBL4525995 | 0.83 | KCNA5 (0.78) | KCNA5 | |
| SCHEMBL4525602 | 0.80 | KCNA5 (1.00) | KCNA5 | |
| SCHEMBL4540539 | 0.80 | KCNA5 (1.00) | KCNA5 | |
| SCHEMBL12694652 | 0.80 | KCNA5 (0.78) | KCNA5 | |
| SCHEMBL4541787 | 0.80 | KCNA5 (1.00) | KCNA5 | |
| SCHEMBL4534593 | 0.80 | KCNA5 (1.00) | KCNA5 | |
| SCHEMBL4526118 | 0.80 | KCNA5 (0.85) | KCNA5 | |
| SCHEMBL4533882 | 0.79 | KCNA5 (1.00) | KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909572-A2 | POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2008-04-16 | — | — | EP | claimed |
| WO-2007015775-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2007-02-08 | — | — | WO | claimed |