SCHEMBL4940382

SCHEMBL4940382

CCCCc1ccc(N(c2ccc(C=Cc3cc[c]cc3)cc2)c2cccc([S+](C)C)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
KDM4A O75164 2/20 0.30
KDM2A Q9Y2K7 2/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
PTAFR P25105 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14488416 0.84 APP (0.33) SPHK1CYP3A4CYP2D6CYP2C9PTAFR
Trifluoromethanesulfonic Acid SCHEMBL4870192 0.82 KCNH2 (0.38) CA2
Trifluoromethanesulfonic Acid SCHEMBL4870169 0.82 KCNH2 (0.38) CA2
Trifluoromethanesulfonic Acid SCHEMBL4870182 0.82 HPGD (0.33) SPHK1CYP3A4CYP2D6CYP2C9CA2
SCHEMBL4941173 0.76
SCHEMBL7718254 0.76 CYP3A4 (0.49) SPHK1CYP3A4CYP2D6CYP2C9CA1
SCHEMBL9915627 0.76 CYP3A4 (0.49) SPHK1CYP3A4CYP2D6CYP2C9CA1
Trifluoromethanesulfonic Acid SCHEMBL3370747 0.76 KCNH2 (0.33)
Trifluoromethanesulfonic Acid SCHEMBL3370751 0.76 CYSLTR2 (0.33)
Trifluoromethanesulfonic Acid SCHEMBL3370743 0.76 KCNH2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390664-A4 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES UNIV ARIZONA (US) 2008-01-02 EP disclosed
EP-1390664-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES The Arizona Board of Regents (US) 2004-02-25 EP disclosed
WO-2002079691-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2002-10-10 WO disclosed