Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL344659 | 0.96 | CA4 (0.47) | — | |
| Glycine SCHEMBL31753874 | 0.92 | — | — | |
| Glycine SCHEMBL4661565 | 0.92 | — | — | |
| Glycine SCHEMBL28640500 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL3863149 | 0.92 | — | — | |
| Glycine SCHEMBL5163282 | 0.92 | — | — | |
| Glycine SCHEMBL5187484 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL6753488 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL2405749 | 0.92 | — | — | |
| Glycine SCHEMBL8069601 | 0.92 | CA4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146641-A1 | ANTIBACTERIAL COMPOSITION | URANO TERUO | 2008-06-19 | — | — | US | disclosed |
| US-20040127535-A1 | containing either a calcium oxide or calcium hydroxide alpha -amino acid chelate compound or both | MURAKASHI LIME INDUSTRY CO., LTD. (JP) | 2004-07-01 | — | — | US | disclosed |