Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RAD52 | P43351 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 12/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948317 | 0.93 | POLB (0.58) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4940719 | 0.89 | KDM1A (0.55) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4934135 | 0.87 | KDM1A (0.48) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4938779 | 0.86 | KDM1A (0.52) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4910290 | 0.82 | TOP2A (0.55) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4933340 | 0.81 | KDM1A (0.57) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4936777 | 0.81 | KDM1A (0.46) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4933388 | 0.80 | KDM1A (0.49) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL17154456 | 0.77 | KDM1A (0.70) | KMT2APOLBRAD52KDM4EMAPT | |
| SCHEMBL4937726 | 0.77 | KDM1A (0.46) | KMT2APOLBRAD52KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | KMT2A 288/4885POLB 178/4885RAD52 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.