Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982149 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL9804614 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL10894979 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL983826 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL789269 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL983629 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL10804165 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL11779391 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL984105 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL1837139 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036454-A1 | POLY (ARYLENE ETHER) COPOLYMER | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-03-27 | — | — | WO | claimed |
| US-20080076884-A1 | POLY(ARYLENE ETHER) COMPOSITION AND METHOD | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-03-27 | — | — | US | claimed |
| US-20080085989-A1 | POLY(ARYLENE ETHER) COPOLYMER | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-04-10 | — | — | US | disclosed |
| US-20080076885-A1 | POLY(ARYLENE ETHER) COMPOSITION AND METHOD | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-03-27 | — | — | US | disclosed |
| WO-2008036454-A1 | POLY (ARYLENE ETHER) COPOLYMER | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-03-27 | — | — | WO | disclosed |
| US-20080076884-A1 | POLY(ARYLENE ETHER) COMPOSITION AND METHOD | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-03-27 | — | — | US | disclosed |