Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737500 | 0.85 | HRH3 (0.42) | HRH3KCNH2HRH1 | |
| SCHEMBL736866 | 0.83 | HRH3 (0.43) | HRH3KCNH2HRH1 | |
| SCHEMBL736063 | 0.75 | HRH3 (0.43) | HRH3KCNH2HRH1 | |
| SCHEMBL736905 | 0.73 | HRH3 (0.45) | HRH3KCNH2 | |
| SCHEMBL737473 | 0.72 | HRH3 (0.41) | HRH3 | |
| SCHEMBL738432 | 0.72 | HRH3 (0.44) | HRH3KCNH2HRH1 | |
| SCHEMBL735700 | 0.72 | HRH3 (0.45) | HRH3KCNH2HRH1 | |
| SCHEMBL738185 | 0.71 | HRH3 (0.47) | HRH3KCNH2HRH1ADRA1A | |
| SCHEMBL736550 | 0.71 | HRH3 (0.43) | HRH3KCNH2HRH1 | |
| SCHEMBL736993 | 0.71 | HRH3 (0.42) | HRH3KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892241-A1 | NOVEL PIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-02-27 | — | — | EP | disclosed |