Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 1.00 |
| ▸ | PTAFR | P25105 | 1/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809351 | 0.98 | HRH3 (1.00) | HRH3PTAFRKCNH2 | |
| SCHEMBL3724043 | 0.97 | HRH3 (0.98) | HRH3PTAFRKCNH2 | |
| SCHEMBL3725408 | 0.96 | HRH3 (0.93) | HRH3PTAFRKCNH2 | |
| SCHEMBL3668224 | 0.96 | HRH3 (0.92) | HRH3PTAFRKCNH2 | |
| SCHEMBL3724608 | 0.95 | HRH3 (0.90) | HRH3PTAFRKCNH2 | |
| SCHEMBL4945297 | 0.93 | HRH3 (0.90) | HRH3PTAFRKCNH2 | |
| SCHEMBL3667994 | 0.90 | HRH3 (0.81) | HRH3PTAFRKCNH2 | |
| SCHEMBL3667652 | 0.90 | HRH3 (0.81) | HRH3PTAFRKCNH2 | |
| SCHEMBL3667649 | 0.90 | HRH3 (0.81) | HRH3PTAFRKCNH2 | |
| SCHEMBL3667998 | 0.90 | HRH3 (0.81) | HRH3PTAFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-11-27 | — | — | US | claimed |
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | HRH4, HRH3, HRH2 | HRH3 2/4885PTAFR 841/4885KCNH2 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.