Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17935736 | 0.85 | APEX1 (0.54) | SMN1; SMN2GLAMAPTAPEX1PDE4A | |
| SCHEMBL29251516 | 0.76 | MAPT (0.47) | SMN1; SMN2GLAMAPTAPEX1PDE4A | |
| SCHEMBL1560781 | 0.73 | CYP3A4 (0.54) | SMN1; SMN2GLAMAPTAPEX1PDE4A | |
| SCHEMBL11637084 | 0.72 | MAPT (0.53) | MAPTAPEX1PDE4AADORA2APDE4B | |
| SCHEMBL17935673 | 0.72 | APEX1 (0.42) | SMN1; SMN2GLAMAPTAPEX1PDE4A | |
| SCHEMBL559878 | 0.72 | MAPT (0.50) | SMN1; SMN2GLAMAPTPDE4AADORA2A | |
| SCHEMBL31098153 | 0.69 | HTT (0.49) | SMN1; SMN2MAPTAPEX1ADORA2BKDM4E | |
| SCHEMBL27714037 | 0.69 | HTT (0.49) | SMN1; SMN2MAPTAPEX1ADORA2BKDM4E | |
| SCHEMBL10946843 | 0.69 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAMAPTAPEX1ADORA2A | |
| SCHEMBL19784137 | 0.68 | SMN1; SMN2 (0.39) | SMN1; SMN2GLAMAPTPDE4AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530576-B1 | HETEROCYCLIC HALAMINE-SUBSTITUTED SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS | UNIV AUBURN (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20080003438-A1 | Heterocyclic siloxanes for use in biocidal coatings and materials | AUBURN UNIVERSITY (US) | 2008-01-03 | — | — | US | disclosed |
| US-6969769-B2 | N-halamine siloxanes for use in biocidal coatings and materials | VANSON HALOSOURCE, INC. (US) | 2005-11-29 | — | — | US | disclosed |
| EP-1530576-A2 | HETEROCYCLIC HALAMINE-SUBSTITUTED SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS | Auburn University (US) | 2005-05-18 | — | — | EP | disclosed |
| US-20040127667-A1 | N-halamine siloxanes for use in biocidal coatings and materials | AUBURN UNIVERSITY | 2004-07-01 | — | — | US | disclosed |
| WO-2003106466-A2 | N-HALAMINE SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS | AUBURN UNIVERSITY (US) | 2003-12-24 | — | — | WO | disclosed |