Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.69 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.69 |
| ▸ | SRC | P12931 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.69 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.69 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.69 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.67 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.67 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.67 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.66 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.66 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.66 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051599 | 1.00 | P2RY1 (0.69) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL30903856 | 0.93 | P2RY1 (0.68) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL347342 | 0.93 | P2RY1 (0.68) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL17148064 | 0.92 | P2RY1 (0.67) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| Adenosine Phosphate SCHEMBL15671063 | 0.91 | P2RY1 (0.76) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL18423487 | 0.89 | P2RY1 (0.73) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| Adenosine Triphosphate SCHEMBL3515197 | 0.88 | P2RY1 (0.70) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL21067651 | 0.86 | P2RY1 (0.60) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL27695784 | 0.86 | P2RY1 (0.63) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| Adenosine Phosphate SCHEMBL1050410 | 0.86 | P2RY1 (0.76) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732365-B2 | Biosynthesis of paclitaxel intermediate | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732365-B2 | Biosynthesis of paclitaxel intermediate | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150284751-A1 | BIOSYNTHESIS OF PACLITAXEL INTERMEDIATE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2015-10-08 | — | — | US | disclosed |
| US-20150284751-A1 | BIOSYNTHESIS OF PACLITAXEL INTERMEDIATE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2015-10-08 | — | — | US | disclosed |
| EP-1232285-B1 | CATALYTIC RNAs WITH AMINOACYLATION ACTIVITY | UNIV NEW YORK STATE RES FOUND (US) | 2008-06-04 | — | — | EP | disclosed |
| US-7001723-B1 | Catalytic RNAs with aminoacylation activity | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-02-21 | — | — | US | disclosed |
| EP-1232285-A1 | CATALYTIC RNAs WITH AMINOACYLATION ACTIVITY | The Research Foundation Of State University of New York (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001038582-A1 | CATALYTIC RNAs WITH AMINOACYLATION ACTIVITY | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2001-05-31 | — | — | WO | disclosed |