Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726628 | 1.00 | HRH3 (0.73) | HRH3KCNH2CSF1RLMNAHTT | |
| SCHEMBL4937192 | 0.95 | HRH3 (0.65) | HRH3KCNH2CSF1RLMNAHTT | |
| SCHEMBL3720942 | 0.93 | HRH3 (0.65) | HRH3KCNH2CSF1R | |
| SCHEMBL3731384 | 0.89 | HRH3 (0.75) | HRH3KCNH2LMNAHTTALDH1A1 | |
| SCHEMBL3731377 | 0.89 | HRH3 (0.75) | HRH3KCNH2LMNAHTTALDH1A1 | |
| SCHEMBL4941878 | 0.86 | HRH3 (0.73) | HRH3KCNH2CSF1R | |
| SCHEMBL3722065 | 0.86 | HRH3 (0.73) | HRH3KCNH2CSF1R | |
| SCHEMBL3672139 | 0.85 | HRH3 (0.73) | HRH3KCNH2 | |
| SCHEMBL3672136 | 0.85 | HRH3 (0.73) | HRH3KCNH2 | |
| SCHEMBL3666051 | 0.85 | HRH3 (1.00) | HRH3KCNH2LMNAHTTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-11-27 | — | — | US | claimed |
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | HRH4, HRH3, HRH2 | HRH3 2/4885KCNH2 581/4885CSF1R 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.