Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 4/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 4/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947877 | 0.84 | PIK3CD (0.38) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2997024 | 0.84 | PIK3CD (0.42) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2997017 | 0.84 | PIK3CD (0.42) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4084032 | 0.82 | DYRK3 (0.54) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL5224962 | 0.82 | PIK3CD (0.49) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4084039 | 0.82 | DYRK3 (0.54) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4866363 | 0.82 | PIK3CD (0.49) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2988218 | 0.82 | PIK3CD (0.40) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2988216 | 0.82 | PIK3CD (0.40) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2991417 | 0.81 | PIK3CD (0.50) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885362-A2 | NOVEL CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006127458-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-30 | — | — | WO | disclosed |