SCHEMBL4946181

SCHEMBL4946181

O=C(O)C=Cc1ccc(-c2ccc(C=CC(=O)O)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.71
CA12 O43570 2/20 0.71
AKR1B10 O60218 2/20 0.71
CA1 P00915 2/20 0.71
CA2 P00918 2/20 0.71
CA3 P07451 2/20 0.71
AKR1B1 P15121 2/20 0.71
CA4 P22748 2/20 0.71
CA6 P23280 2/20 0.71
DPP4 P27487 2/20 0.71
CA5A P35218 2/20 0.71
CA7 P43166 2/20 0.71
CA9 Q16790 2/20 0.71
CA14 Q9ULX7 2/20 0.71
CA5B Q9Y2D0 2/20 0.71
ESR1 P03372 1/20 0.71
PKM P14618 1/20 0.71
TYR P14679 1/20 0.71
ESR2 Q92731 1/20 0.71
HDAC2 Q92769 5/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4946176 1.00 HCAR2 (0.71) HCAR2CA12AKR1B10CA1CA2
SCHEMBL165795 0.93 HDAC2 (0.75) HCAR2CA12AKR1B10CA1CA2
SCHEMBL165794 0.93 HDAC2 (0.75) HCAR2CA12AKR1B10CA1CA2
SCHEMBL68395 0.92 HCAR2 (0.81) HCAR2CA12AKR1B10CA1CA2
SCHEMBL14081549 0.92 HCAR2 (0.81) HCAR2CA12AKR1B10CA1CA2
SCHEMBL713717 0.92 HCAR2 (0.81) HCAR2CA12AKR1B10CA1CA2
SCHEMBL3293835 0.91 ESR1 (0.88) HCAR2CA12AKR1B10CA1CA2
SCHEMBL3293830 0.91 ESR1 (0.88) HCAR2CA12AKR1B10CA1CA2
Hydrochloric Acid SCHEMBL5066651 0.91 HDAC2 (0.72) HCAR2CA12AKR1B10CA1CA2
SCHEMBL18662489 0.90 HCAR2 (0.77) HCAR2CA12AKR1B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838543-A Photopolymer composition containing organic silicon film forming agent and grating 杭州光粒科技有限公司 2023-03-24 CN claimed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN claimed
CN-118063664-A Preparation method of ultrahigh heat-resistant ethylene-tetrafluoroethylene copolymer 内蒙古氟源科技有限公司 2024-05-24 CN disclosed
CN-116391001-A Curable composition and cured product thereof 日产化学株式会社 2023-07-04 CN disclosed
CN-115838543-A Photopolymer composition containing organic silicon film forming agent and grating 杭州光粒科技有限公司 2023-03-24 CN disclosed
CN-113527929-B Photopolymer composition and optical grating 杭州光粒科技有限公司 2023-02-03 CN disclosed
CN-112759698-B Photopolymer composition, transmission type diffraction grating and preparation method thereof 杭州光粒科技有限公司 2023-01-10 CN disclosed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN disclosed
CN-114527629-B Super-resolution photoetching method based on double dark spot combined inhibition and photoresist 之江实验室 2022-08-05 CN disclosed
WO-2022118745-A1 LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2022-06-09 WO disclosed
CN-114527629-A Super-resolution photoetching method based on double dark spot combined inhibition and photoresist 之江实验室 2022-05-24 CN disclosed
EP-1992984-A2 Liquid crystal display NEC Corporation (JP) 2008-11-19 EP disclosed
EP-1748311-B1 Liquid crystal display NEC CORP (JP) 2008-09-10 EP disclosed
EP-1748311-A2 Liquid crystal display NEC Corporation (JP) 2007-01-31 EP disclosed
EP-0805373-B1 Liquid crystal display NEC CORP (JP) 2006-11-29 EP disclosed
US-6177976-B1 Liquid crystal display NEC CORPORATION (JP) 2001-01-23 US disclosed
US-6160604-A Liquid crystal display with pixel electrode having aperture containing additional electrode NEC CORPORATION (JP) 2000-12-12 US disclosed
US-5963290-A Liquid crystal display NEC CORPORATION (JP) 1999-10-05 US disclosed
US-5959707-A Liquid crystal display having domains with different tilted-up directions as well as domains with different twist directions of lc molecules NEC CORPORATION (JP) 1999-09-28 US disclosed
EP-0805373-A2 Liquid crystal display NEC CORPORATION (JP) 1997-11-05 EP disclosed