SCHEMBL4947015

SCHEMBL4947015

CCC(OP(=O)([O-])[O-])c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.[Ni+2]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 4/20 0.44
NR1I2 O75469 1/20 0.44
LMNA P02545 2/20 0.40
RECQL P46063 1/20 0.40
GPR55 Q9Y2T6 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GALR3 O60755 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA2 P00918 3/20 0.37
CA1 P00915 2/20 0.37
GAA P10253 2/20 0.37
CYP1A2 P05177 3/20 0.36
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28660343 0.97 HMGCR (0.44) HMGCRNR1I2LMNARECQLGPR55
SCHEMBL3140206 0.85 HMGCR (0.46) HMGCRNR1I2LMNARECQLGPR55
Calcium SCHEMBL7746280 0.84 HMGCR (0.45) HMGCRNR1I2LMNARECQLGPR55
SCHEMBL8659395 0.78 HMGCR (0.43) HMGCRNR1I2LMNARECQLMEN1
SCHEMBL31688381 0.78 HMGCR (0.43) HMGCRNR1I2LMNARECQLMEN1
SCHEMBL9162616 0.77 HMGCR (0.38) HMGCRNR1I2LMNARECQLGPR55
SCHEMBL911831 0.75 HMGCR (0.43) HMGCRNR1I2LMNARECQLMEN1
Potassium Ion SCHEMBL5912033 0.75 HMGCR (0.43) HMGCRNR1I2LMNARECQLMEN1
Zinc Ion SCHEMBL915462 0.75 HMGCR (0.43) HMGCRNR1I2LMNARECQLMEN1
SCHEMBL563208 0.75 HMGCR (0.43) HMGCRNR1I2LMNARECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1174737-B1 Optical compensation sheet and liquid crystal display KONICA CORP (JP) 2008-11-05 EP disclosed
US-7199848-B2 Optical compensation sheet and liquid crystal display KONICA CORPORATION (JP) 2007-04-03 US disclosed
US-7158200-B2 Optical compensation sheet and liquid crystal display KONICA CORPORATION (JP) 2007-01-02 US disclosed
US-20040080693-A1 Optical compensation sheet and liquid crystal display KONICA CORPORATION 2004-04-29 US disclosed
US-20020041352-A1 Optical compensation sheet and liquid crystal display KONICA CORPORATION 2002-04-11 US disclosed
EP-1174737-A2 Optical compensation sheet and liquid crystal display KONICA CORPORATION (JP) 2002-01-23 EP disclosed
US-6068794-A ORGANONITROGEN POLYMER KONICA CORPORATION (JP) 2000-05-30 US disclosed
EP-0761788-B1 Protective film for polarizing plate KONISHIROKU PHOTO IND (JP) 1999-10-20 EP disclosed
US-5914073-A POLYMER COATING ON PLATE WITH ARYLATE MONOMERS IN FILM KONICA CORPORATION (JP) 1999-06-22 US disclosed
EP-0761788-A1 Protective film for polarizing plate KONICA CORPORATION (JP) 1997-03-12 EP disclosed