⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334339 | 0.74 | — | — | |
| SCHEMBL9337168 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL8141605 | 0.67 | — | — | |
| SCHEMBL19629212 | 0.65 | MEN1 (0.33) | — | |
| SCHEMBL878822 | 0.64 | — | — | |
| SCHEMBL14111830 | 0.62 | — | — | |
| SCHEMBL10964925 | 0.62 | — | — | |
| SCHEMBL19625984 | 0.60 | — | — | |
| SCHEMBL826097 | 0.58 | — | — | |
| SCHEMBL6444775 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | claimed |
| US-5763431-A | MODIFIED NEUROACTIVE STEROID | JACKSON MEYER B (US) | 1998-06-09 | — | — | US | claimed |
| US-RE35517-E | PROGESTERONE DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1997-05-20 | — | — | US | claimed |
| WO-1995005826-A1 | METHOD FOR REGULATING NEUROPEPTIDE HORMONE SECRETION | JACKSON MEYER B (US) | 1995-03-02 | — | — | WO | claimed |
| CN-1090493-A | diuretic | BOEHRINGER INGELHEIM KG (DE) | 1994-08-10 | — | — | CN | claimed |
| US-5208227-A | Stress relieving and anxiety modulators | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1993-05-04 | — | — | US | claimed |
| US-5120723-A | Alleviate stress, anxiety, seizures | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1992-06-09 | — | — | US | claimed |
| EP-0458312-A1 | Novel cyclobutane derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-11-27 | — | — | EP | claimed |
| JP-4297463-A | — | — | None | — | — | JP | disclosed |
| US-8658677-B2 | Pyridyl-2-methylamino compounds, compositions and uses thereof | ARIA NEUROSCIENCES INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-20130079376-A1 | PYRIDYL-2-METHYLAMINO COMPOUNDS, COMPOSITIONS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-03-28 | — | — | US | disclosed |
| US-20100210695-A1 | COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS | DARA BIOSCIENCES, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20080311036-A1 | Imaging of Neural and Organ Injury or Damage | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-12-18 | — | — | US | disclosed |
| US-20080161395-A1 | Derivatives of Aminobutanoic Acid Inhibiting Cpt | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-07-03 | — | — | US | disclosed |
| US-5116861-A | Treatment of Hypertension and Angina Pectoris | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0458312-A1 | Novel cyclobutane derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0458312-A1 | Novel cyclobutane derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0412699-A2 | Nitrosothiol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-02-13 | — | — | EP | disclosed |
| US-4804665-A | NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-14 | — | — | US | disclosed |
| EP-0273659-A1 | Azaspiro compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |