Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.52 |
| ▸ | RHOC | P08134 | 1/20 | 0.48 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097423 | 0.82 | F10 (0.56) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL10282497 | 0.81 | F10 (0.55) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1096846 | 0.81 | F10 (0.53) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1106589 | 0.79 | F10 (0.53) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1096299 | 0.78 | F10 (0.48) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1096804 | 0.77 | F10 (0.52) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1095983 | 0.77 | F10 (0.51) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1096188 | 0.77 | F10 (0.53) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1097619 | 0.77 | F10 (0.53) | F10RHOCRHOAHPGDTP53 | |
| SCHEMBL1098342 | 0.73 | F10 (0.49) | F10RHOCRHOAHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |