SCHEMBL4947716

SCHEMBL4947716

N=C(N)NCCC[C@H](NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
MPO P05164 1/20 0.56
MAPT P10636 1/20 0.56
TSHR P16473 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
KMT2A Q03164 1/20 0.56
HIF1A Q16665 1/20 0.56
ACE P12821 2/20 0.53
ECE1 P42892 4/20 0.49
ALOX15 P16050 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4947728 1.00 KDM4E (0.56) KDM4EMEN1LMNAMPOMAPT
SCHEMBL13605071 1.00 KDM4E (0.56) KDM4EMEN1LMNAMPOMAPT
SCHEMBL29799941 0.98 KDM4E (0.54) KDM4EMEN1LMNAMPOMAPT
SCHEMBL30839329 0.97 KDM4E (0.53) KDM4EMEN1LMNAMPOMAPT
SCHEMBL30148431 0.96 KDM4E (0.52) KDM4EMEN1LMNAMPOMAPT
SCHEMBL30305304 0.96 KDM4E (0.52) KDM4EMEN1LMNAMPOMAPT
SCHEMBL29732484 0.96 KDM4E (0.52) KDM4EMEN1LMNAMPOMAPT
SCHEMBL30305288 0.96 KDM4E (0.52) KDM4EMEN1LMNAMPOMAPT
SCHEMBL30305639 0.96 KDM4E (0.52) KDM4EMEN1LMNAMPOMAPT
SCHEMBL29800140 0.96 KDM4E (0.52) KDM4EMEN1LMNAMPOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646203-A1 C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID Dompé farmaceutici SpA (IT) 2025-11-12 EP claimed
WO-2024146922-A1 C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID DOMPE' FARMACEUTICI SPA (IT) 2024-07-11 WO claimed
EP-4646203-A1 C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID Dompé farmaceutici SpA (IT) 2025-11-12 EP disclosed
WO-2024146922-A1 C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID DOMPE' FARMACEUTICI SPA (IT) 2024-07-11 WO disclosed
CN-102477068-A Amino acid derivative for preparing thrombus dissolving medicament, and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-05-30 CN disclosed
EP-1910322-A2 NOVEL BENZO [D][1,3]-DIOXOL DERIVATIVES Concert Pharmaceuticals Inc. (US) 2008-04-16 EP disclosed
WO-2007016431-A2 NOVEL BENZO [D] [1,3]-DIOXOL DERIVATIVES CONCERT PHARMACEUTICALS INC. (US) 2007-02-08 WO disclosed