Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097033 | 0.81 | F10 (0.35) | F10F2 | |
| SCHEMBL1097031 | 0.81 | F10 (0.35) | F10F2 | |
| SCHEMBL1096402 | 0.78 | KDM4E (0.43) | F10KDM4ELMNAMAPK1 | |
| SCHEMBL1100907 | 0.78 | ITGB1 (0.41) | F10KDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL1095756 | 0.77 | F10 (0.45) | F10SMN1; SMN2F2 | |
| SCHEMBL1095757 | 0.77 | F10 (0.45) | F10SMN1; SMN2F2 | |
| SCHEMBL1095197 | 0.77 | KDM4E (0.46) | F10KDM4ELMNAMAPK1 | |
| SCHEMBL1096175 | 0.75 | KDM4E (0.44) | KDM4ELMNASMN1; SMN2MAPK1HDAC3 | |
| SCHEMBL1097081 | 0.74 | KDM4E (0.40) | F10KDM4ELMNAMAPK1 | |
| SCHEMBL1097037 | 0.73 | F10 (0.35) | F10KDM4ESMN1; SMN2F2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |