SCHEMBL4948145

SCHEMBL4948145

CC(=O)N1C=NCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16541693 0.86
SCHEMBL31470922 0.77
SCHEMBL1059408 0.76
SCHEMBL9215113 0.76
SCHEMBL11544540 0.76
Ethaneperoxoic Acid SCHEMBL31288482 0.74
SCHEMBL11791853 0.73 DPP4 (0.34)
SCHEMBL427806 0.67
Acetic Acid SCHEMBL31591661 0.67 CA1 (0.38)
SCHEMBL9178658 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108370061-B Solid electrolyte composition, binder particle, all-solid-state secondary battery, sheet, electrode sheet, and method for producing same 富士胶片株式会社 2021-12-31 CN disclosed
CN-113135908-A Preparation method of tizanidine hydrochloride 杭州泓友医药科技有限公司 2021-07-20 CN disclosed
EP-1918287-A2 LPA receptor agonists and antagonists and methods of use THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2008-05-07 EP disclosed
EP-1263752-B1 LPA RECEPTOR AGONISTS AND ANTAGONISTS AND METHODS OF USE UNIV TENNESSEE RES CORP (US) 2007-12-05 EP disclosed
EP-1427424-A4 LPA RECEPTOR AGONISTS AND ANTAGONISTS AND METHODS OF USE UNIV TENNESSEE RES CORP (US) 2006-12-13 EP disclosed
US-20050261252-A1 LPA receptor agonists and antagonists and methods of use MILLER DUANE D 2005-11-24 US disclosed
US-6875757-B2 For therapy of cancer, enhancing cell proliferation, and wound UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-04-05 US disclosed
EP-1427424-A2 LPA RECEPTOR AGONISTS AND ANTAGONISTS AND METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2004-06-16 EP disclosed
EP-1263752-A4 LPA RECEPTOR AGONISTS AND ANTAGONISTS AND METHODS OF USE UNIV TENNESSEE RES CORP (US) 2003-07-30 EP disclosed
US-20030130237-A1 LPA receptor agonists and antagonists and methods of use MILLER DUANE D (US) 2003-07-10 US disclosed
WO-2001071022-A2 LPA RECEPTOR AGONISTS AND ANTAGONISTS AND METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2001-09-27 WO disclosed
US-5237072-A Contacting an imidazoline sulfonic acid with at least one amine component in presence of alcohol-containing liquid ALLERGAN, INC. (US) 1993-08-17 US disclosed
US-5130441-A Reaction of an imidazoline sulfonic acid with an amine in the presence of an alcohol ALLERGAN, INC. (US) 1992-07-14 US disclosed
EP-0081923-B1 2-(TRISUBSTITUTED PHENYLIMINO)-IMIDAZOLINES ALCON LABORATORIES, INC. (US) 1987-01-21 EP disclosed
EP-0081924-B1 TOPICAL COMPOSTIONS FOR LOWERING INTRAOCULAR PRESSURE ALCON LABORATORIES, INC. (US) 1986-02-19 EP disclosed
US-4517199-A TREATMENT OF GLAUCOMA ALCON LABORATORIES, INC. (US) 1985-05-14 US disclosed
US-4515800-A GLAUCOMA ALCON MANUFACTURING, LTD. 1985-05-07 US disclosed
US-4461904-A 2-(Trisubstituted phenylimino)-imidazolines ALCON LABORATORIES, INC. (US) 1984-07-24 US disclosed
EP-0081923-A2 2-(Trisubstituted phenylimino)-imidazolines ALCON LABORATORIES, INC. (US) 1983-06-22 EP disclosed
EP-0081924-A1 Topical compostions for lowering intraocular pressure ALCON LABORATORIES, INC. (US) 1983-06-22 EP disclosed