Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 1.00 |
| ▸ | SCARB1 | Q8WTV0 | 7/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948990 | 0.90 | MAPK14 (1.00) | MAPK14SCARB1 | |
| SCHEMBL4948529 | 0.87 | MAPK14 (0.82) | MAPK14SCARB1GSK3A | |
| SCHEMBL4952957 | 0.86 | MAPK14 (0.83) | MAPK14SCARB1 | |
| SCHEMBL4956669 | 0.86 | MAPK14 (0.75) | MAPK14SCARB1 | |
| SCHEMBL4943425 | 0.85 | MAPK14 (0.82) | MAPK14SCARB1 | |
| SCHEMBL4944578 | 0.85 | MAPK14 (1.00) | MAPK14SCARB1 | |
| SCHEMBL4949559 | 0.82 | MAPK14 (0.73) | MAPK14SCARB1 | |
| SCHEMBL12669850 | 0.81 | MAPK14 (0.74) | MAPK14SCARB1 | |
| SCHEMBL4947294 | 0.78 | MAPK14 (0.73) | MAPK14SCARB1GSK3A | |
| SCHEMBL12669854 | 0.78 | MAPK14 (0.67) | MAPK14SCARB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |