Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948596 | 0.90 | AURKA (0.43) | AURKAAURKB | |
| SCHEMBL4946077 | 0.76 | ITK (0.37) | AURKAAURKB | |
| SCHEMBL4949158 | 0.69 | AURKA (0.42) | AURKAAURKB | |
| SCHEMBL4827138 | 0.67 | AURKA (0.40) | AURKAAURKB | |
| SCHEMBL4948961 | 0.67 | AURKA (0.53) | AURKAAURKB | |
| SCHEMBL4965819 | 0.66 | AURKA (0.35) | AURKAAURKB | |
| SCHEMBL4827132 | 0.66 | AURKA (0.44) | AURKAAURKB | |
| SCHEMBL4950836 | 0.65 | AURKA (0.40) | AURKAAURKB | |
| SCHEMBL4948278 | 0.65 | AURKA (0.42) | AURKAAURKB | |
| SCHEMBL4891748 | 0.65 | PAK4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885725-B1 | TRICYCLIC AZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-09-24 | — | — | EP | disclosed |