SCHEMBL4950446

SCHEMBL4950446

C=[Zr](Cl)(Cl)(C1C=CC2=C1CCCC2)C1C=CC2=C1CCCC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15168105 0.80
SCHEMBL846717 0.77
SCHEMBL376316 0.77
SCHEMBL4364583 0.77
SCHEMBL60124 0.77
SCHEMBL7624635 0.75
SCHEMBL2425038 0.73
SCHEMBL7556930 0.73
SCHEMBL7770844 0.73
Bromide SCHEMBL7770456 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12491207-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability VANELTIX PHARMA, INC. (US) 2025-12-09 US disclosed
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2023-05-04 US disclosed
US-11491179-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability URIGEN PHARMACEUTICALS, INC. (US) 2022-11-08 US disclosed
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2021-09-16 US disclosed
EP-3609483-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY Urigen Pharmaceuticals, Inc. (US) 2020-02-19 EP disclosed
WO-2018191412-A9 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. (US) 2019-05-31 WO disclosed
WO-2018191412-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. (US) 2018-10-18 WO disclosed
US-20080281063-A9 Ethylene polymers and copolymers with high optical opacity and methods of making the same SUKHADIA ASHISH M 2008-11-13 US disclosed
US-7094857-B2 Ethylene polymers and copolymers with high optical opacity CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) 2006-08-22 US disclosed
US-20050203265-A1 Ethylene polymers and copolymers with high optical opacity CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2005-09-15 US disclosed
US-20050203261-A1 Ethylene polymers and copolymers with high optical opacity and methods of making the same CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2005-09-15 US disclosed
EP-0754731-B2 Polyamide resin composition MITSUI CHEMICALS INC (JP) 2004-12-15 EP disclosed
EP-1153938-A1 CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-14 EP disclosed
US-5883275-A Process for the hydrogenation of metallocenes TARGOR GMBH (DE) 1999-03-16 US disclosed
EP-0733652-A1 NOVEL OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING OLEFIN BY USING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1996-09-25 EP disclosed
EP-0283164-B1 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL IND (JP) 1995-05-24 EP disclosed
US-5371146-A A blends of ethylene-(alpha)olefins copolymers has high transparency, high strength, blocking resistance, good melt flowability and tension MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5008356-A Copolymerization using coordination catalysts MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-04-16 US disclosed
US-5003019-A Radiation transparent, heat resistant, solvent resistant copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-03-26 US disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed