Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955570 | 0.83 | SLC6A2 (0.72) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3987204 | 0.83 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL3952511 | 0.82 | SLC6A2 (0.71) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27676023 | 0.82 | SLC6A2 (0.74) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27672130 | 0.82 | SLC6A2 (0.74) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4949055 | 0.81 | SLC6A2 (0.42) | SLC6A2SLC6A3 | |
| SCHEMBL3954397 | 0.80 | SLC6A2 (0.62) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4953732 | 0.79 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4951469 | 0.79 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4956786 | 0.79 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419980-B2 | Fused-aryl and heteroaryl derivatives and methods of their use | WYETH (US) | 2008-09-02 | — | — | US | disclosed |