SCHEMBL4952136

SCHEMBL4952136

O=C(O)COCC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4952337 0.89 TSHR (0.38)
SCHEMBL2262348 0.87
SCHEMBL4947787 0.87 HSD17B10 (0.38)
SCHEMBL26928 0.84
Water SCHEMBL8146640 0.81 TSHR (0.50)
Ammonia Solution, Strong SCHEMBL11325580 0.81 TSHR (0.50)
SCHEMBL7522993 0.81 TSHR (0.50)
SCHEMBL516734 0.81 TSHR (0.50)
Ammonia Solution, Strong SCHEMBL11325579 0.81 TSHR (0.50)
SCHEMBL11884627 0.81 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080146768-A1 PROCESSES FOR PREPARING POLYMERS USING ALPHA,OMEGA-DIFUNCTIONAL ALDARAMIDES E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-19 US disclosed
EP-1858955-A1 PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-11-28 EP disclosed
US-20060264672-A1 Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers E. I. DU PONT DE NEMOURS AND COMPANY 2006-11-23 US disclosed
WO-2006091901-A1 PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-08-31 WO disclosed
US-5292937-A Use of malonic acid derivative compounds for retarding plant growth RHONE-POULENC INC. (US) 1994-03-08 US disclosed
US-5123951-A Ethylene response inducing agent and malonic acid derivative RHONE-POULENC NEDERLAND B.V. (NL) 1992-06-23 US disclosed
EP-0262209-A1 SYNERGISTIC PLANT GROWTH REGULATOR COMPOSITIONS. RHONE POULENC BV (NL) 1988-04-06 EP disclosed
WO-1987005781-A2 SYNERGISTIC PLANT GROWTH REGULATOR COMPOSITIONS RHONE-POULENC NEDERLANDS B.V. (NL) 1987-10-08 WO disclosed