Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 17/20 | 0.49 |
| ▸ | HRH1 | P35367 | 8/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955770 | 0.92 | SSTR5 (0.60) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4952100 | 0.92 | SSTR5 (0.48) | SSTR5HRH1SSTR1KCNH2 | |
| SCHEMBL4958195 | 0.83 | SSTR5 (0.46) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4957108 | 0.82 | SSTR5 (0.46) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4953000 | 0.80 | SSTR5 (0.55) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4955267 | 0.79 | SSTR5 (0.55) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4952997 | 0.78 | SSTR5 (0.60) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4946999 | 0.76 | SSTR5 (0.47) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4956829 | 0.76 | SSTR5 (0.45) | SSTR5HRH1HTR2B | |
| SCHEMBL3580190 | 0.75 | SSTR5 (0.83) | SSTR5HRH1HTR2BSSTR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858901-B1 | BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2008-11-05 | — | — | EP | disclosed |