Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152962 | 0.96 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL25224472 | 0.94 | NPC1 (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL7147757 | 0.91 | MAPT (0.51) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL25230007 | 0.90 | NPC1 (0.43) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10033262 | 0.89 | NPC1 (0.51) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL25226767 | 0.89 | MAPT (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL25225206 | 0.89 | NPC1 (0.42) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL30457272 | 0.89 | NPC1 (0.42) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL3792053 | 0.88 | POLB (0.56) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14500157 | 0.88 | NPC1 (0.49) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| EP-1689827-B1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| EP-1689827-B1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| EP-1689827-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | Rolic AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005054406-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2005-06-16 | — | — | WO | disclosed |