SCHEMBL4954067

SCHEMBL4954067

Nc1cc2ncn(N)c2cc1N

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
APEX1 P27695 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
FGFR1 P11362 2/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTK2 Q05397 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4955539 0.76 FGFR1 (0.50) MAPTHSD17B10FGFR1
SCHEMBL19848103 0.76 POLB (0.50) ALDH1A1KDM4EMEN1NPC1POLB
SCHEMBL4953951 0.76 MAPT (0.34) MAPTHSD17B10ALDH1A1KDM4EAPEX1
SCHEMBL19848658 0.74 MAPT (0.44) MAPTHSD17B10ALDH1A1KDM4EFGFR1
SCHEMBL19911410 0.74 MAPT (0.58) MAPTHSD17B10ALDH1A1KDM4EFGFR1
SCHEMBL4951916 0.71 FGFR1 (0.36) MAPTHSD17B10ALDH1A1KDM4EAPEX1
SCHEMBL19911336 0.68 FGFR1 (0.42) ALDH1A1FGFR1SMN1; SMN2
SCHEMBL19848148 0.68 BACE1 (0.37) POLB
SCHEMBL15241833 0.68 FGFR1 (0.54) MAPTHSD17B10ALDH1A1KDM4EFGFR1
SCHEMBL19848508 0.68 GFER (0.36) MAPTHSD17B10ALDH1A1KDM4EFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118970382-A Mica composite part for CCS lithium battery cell conducting plate and preparation method thereof 浙江荣泰电工器材股份有限公司 2024-11-15 CN claimed
CN-115651538-B Polyborosilazane/epoxy composite coating resistant to acid salt mist 杭州万观科技有限公司 2023-06-02 CN claimed
CN-115651538-A Polyborosilazane/epoxy composite coating resistant to acid salt mist 杭州万观科技有限公司 2023-01-31 CN claimed
US-7371264-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-05-13 US claimed
US-20060042026-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2006-03-02 US claimed
CN-118970382-A Mica composite part for CCS lithium battery cell conducting plate and preparation method thereof 浙江荣泰电工器材股份有限公司 2024-11-15 CN disclosed
CN-115651538-B Polyborosilazane/epoxy composite coating resistant to acid salt mist 杭州万观科技有限公司 2023-06-02 CN disclosed
CN-115651538-B Polyborosilazane/epoxy composite coating resistant to acid salt mist 杭州万观科技有限公司 2023-06-02 CN disclosed
CN-115651538-A Polyborosilazane/epoxy composite coating resistant to acid salt mist 杭州万观科技有限公司 2023-01-31 CN disclosed
CN-115651538-A Polyborosilazane/epoxy composite coating resistant to acid salt mist 杭州万观科技有限公司 2023-01-31 CN disclosed
US-7371264-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-05-13 US disclosed
EP-1781379-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-05-09 EP disclosed
WO-2006026495-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2006-03-09 WO disclosed
US-20060042026-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060042026-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, KDM5A, KDM5C MAPT 1139/4885HSD17B10 587/4885ALDH1A1 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.