⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688615 | 1.00 | — | — | |
| SCHEMBL7777452 | 1.00 | — | — | |
| SCHEMBL8381180 | 1.00 | — | — | |
| SCHEMBL3478911 | 1.00 | — | — | |
| SCHEMBL16051190 | 1.00 | — | — | |
| SCHEMBL1983125 | 1.00 | — | — | |
| SCHEMBL27753942 | 1.00 | — | — | |
| SCHEMBL14326431 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30177889 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL30187341 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970278-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014139328-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-09-18 | — | — | WO | claimed |
| EP-1924275-B1 | THIO-CONTAINING INHIBITORS OF AMINOPEPTIDASE P, COMPOSITIONS THEREOF AND METHOD OF USE | SIMMONS WILLIAM H (US) | 2012-08-08 | — | — | EP | claimed |
| US-20070060525-A1 | Thio-containing inhibitors of aminopeptidase P, compositions thereof and method of use | SIMMONS WILLIAM H | 2007-03-15 | — | — | US | claimed |
| WO-2024049979-A2 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME | SENDA BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| EP-2970278-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014139328-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-1924275-B1 | THIO-CONTAINING INHIBITORS OF AMINOPEPTIDASE P, COMPOSITIONS THEREOF AND METHOD OF USE | SIMMONS WILLIAM H (US) | 2012-08-08 | — | — | EP | disclosed |
| US-20120101006-A1 | Methods and Compositions for the Production of Orthogonal tRNA-Aminoacyl tRNA Synthetase Pairs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-26 | — | — | US | disclosed |
| US-7741281-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-06-22 | — | — | US | disclosed |
| US-20090227002-A1 | Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs | THE SCRIPPS RESEARCH INSTITUTE and THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-09-10 | — | — | US | disclosed |
| US-7390789-B2 | Thio-containing inhibitors of aminopeptidase P, and compositions thereof | SIMMONS WILLIAM H | 2008-06-24 | — | — | US | disclosed |
| US-7323447-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-29 | — | — | US | disclosed |
| US-20070060525-A1 | Thio-containing inhibitors of aminopeptidase P, compositions thereof and method of use | SIMMONS WILLIAM H | 2007-03-15 | — | — | US | disclosed |