Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949684 | 0.80 | CYP3A4 (0.39) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL4951512 | 0.79 | HTR2C (0.43) | TSHRHPGDHSD17B10TDP1HTR2C | |
| SCHEMBL4952821 | 0.76 | CYP3A4 (0.35) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL4956148 | 0.75 | — | — | |
| SCHEMBL13773249 | 0.73 | CYP3A4 (0.39) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL4955594 | 0.72 | HTR2A (0.33) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL4949260 | 0.72 | SLC6A2 (0.42) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL4953258 | 0.70 | PRKCI (0.34) | HTR2CHTR2A | |
| SCHEMBL4954079 | 0.70 | PDCD1 (0.34) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL4954264 | 0.70 | MKNK1 (0.44) | CYP3A4TSHRALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371264-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-13 | — | — | US | claimed |
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | US | claimed |
| US-7371264-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-13 | — | — | US | disclosed |
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KDM5A, KDM5C | CYP3A4 372/4885TSHR 4818/4885ALDH1A1 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.