Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 13/20 | 0.41 |
| ▸ | GCGR | P47871 | 7/20 | 0.40 |
| ▸ | GIPR | P48546 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956107 | 0.88 | GCGR (0.45) | GCGRGIPR | |
| SCHEMBL4957713 | 0.87 | GCGR (0.47) | GCGRGIPR | |
| SCHEMBL4958938 | 0.86 | GCGR (0.44) | GCGRGIPR | |
| SCHEMBL4959101 | 0.85 | GCGR (0.42) | EIF4EGCGRGIPR | |
| SCHEMBL4955239 | 0.84 | EIF4E (0.42) | EIF4EGCGRGIPR | |
| SCHEMBL4957944 | 0.84 | GCGR (0.48) | GCGRGIPR | |
| SCHEMBL4954768 | 0.83 | GCGR (0.44) | GCGRGIPR | |
| SCHEMBL4956139 | 0.83 | GCGR (0.42) | EIF4EGCGRGIPR | |
| SCHEMBL4957923 | 0.82 | GCGR (0.43) | GCGRGIPR | |
| SCHEMBL4959181 | 0.82 | GCGR (0.42) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200371-A1 | THIAZOLE AND THIADIAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | IMPINJ, INC. | 2008-08-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200371-A1 | THIAZOLE AND THIADIAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | PTPN1, PTPN5, PTPN18 | EIF4E 1915/4885GCGR 2166/4885GIPR 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.