Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 12/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.83 |
| ▸ | MAPT | P10636 | 8/20 | 0.83 |
| ▸ | POLB | P06746 | 8/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.83 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.83 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.83 |
| ▸ | APAF1 | O14727 | 1/20 | 0.83 |
| ▸ | PKM | P14618 | 1/20 | 0.83 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.83 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955393 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL2837896 | 0.90 | PTPN2 (0.81) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL2837903 | 0.90 | PTPN2 (0.81) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL2837901 | 0.90 | PTPN2 (0.81) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL1421364 | 0.85 | PTPN2 (0.74) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL3761481 | 0.85 | PTPN2 (0.74) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL1421366 | 0.85 | PTPN2 (0.74) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL29525393 | 0.85 | PTPN2 (0.74) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL5993845 | 0.83 | PTPN2 (0.71) | PTPN2PTPN1MEN1KMT2AMAPT | |
| SCHEMBL12315854 | 0.82 | MEN1 (0.72) | PTPN2PTPN1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043181-A1 | AUGMENTING STEM CELL POPULATIONS BY MODULATING T-CELL PROTEIN TYROSINE PHOSPHATASE (TC-PTP) | MCGILL UNIVERSITY (CA) | 2008-04-17 | — | — | WO | claimed |
| WO-2008043181-A1 | AUGMENTING STEM CELL POPULATIONS BY MODULATING T-CELL PROTEIN TYROSINE PHOSPHATASE (TC-PTP) | MCGILL UNIVERSITY (CA) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043181-A1 | AUGMENTING STEM CELL POPULATIONS BY MODULATING T-CELL PROTEIN TYROSINE PHOSPHATASE (TC-PTP) | MCGILL UNIVERSITY (CA) | 2008-04-17 | — | — | WO | disclosed |
| US-20060070135-A1 | Compositions and methods for inhibiting the enzymatic activity of PTP-1B | TREMBLAY MICHEL | 2006-03-30 | — | — | US | disclosed |