Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688422 | 0.81 | MAPT (0.49) | ALDH1A1GAAMAPTHTTKMT2A | |
| SCHEMBL10605933 | 0.81 | MAPT (0.49) | ALDH1A1GAAMAPTHTTKMT2A | |
| SCHEMBL2007438 | 0.81 | MAPT (0.49) | ALDH1A1GAAMAPTHTTKMT2A | |
| SCHEMBL2007435 | 0.81 | MAPT (0.49) | ALDH1A1GAAMAPTHTTKMT2A | |
| SCHEMBL16135282 | 0.81 | MAPT (0.49) | ALDH1A1GAAMAPTHTTKMT2A | |
| SCHEMBL23345517 | 0.81 | MAPT (0.49) | ALDH1A1GAAMAPTHTTKMT2A | |
| SCHEMBL16135275 | 0.81 | MAPT (0.49) | ALDH1A1GAAMAPTHTTKMT2A | |
| SCHEMBL6434876 | 0.79 | MAPT (0.50) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL6434868 | 0.79 | MAPT (0.50) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL16135276 | 0.77 | MAPT (0.46) | KDM4EALDH1A1ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402651-B2 | Macromolecular compounds with a core-shell structure | H.C. STARCK GMBH & CO. KG (DE) | 2008-07-22 | — | — | US | disclosed |
| US-20050215760-A1 | Macromolecular compounds with a core-shell structure | H. C. STARCK GMBH (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1580217-A1 | Macromolecular compounds with core-shell structure | H.C. Starck GmbH (DE) | 2005-09-28 | — | — | EP | disclosed |