Thiophene

Thiophene

SCHEMBL4955558

CCCCCCCCCC=Cc1cccs1.c1ccsc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
HTT P42858 1/20 0.45
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
TNNC1 P63316 1/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10605933 0.94 MAPT (0.49) MAPTHTTALDH1A1LMNAGAA
SCHEMBL16135282 0.94 MAPT (0.49) MAPTHTTALDH1A1LMNAGAA
SCHEMBL2007435 0.94 MAPT (0.49) MAPTHTTALDH1A1LMNAGAA
SCHEMBL15688422 0.94 MAPT (0.49) MAPTHTTALDH1A1LMNAGAA
SCHEMBL2007438 0.94 MAPT (0.49) MAPTHTTALDH1A1LMNAGAA
SCHEMBL23345517 0.94 MAPT (0.49) MAPTHTTALDH1A1LMNAGAA
SCHEMBL16135275 0.94 MAPT (0.49) MAPTHTTALDH1A1LMNAGAA
SCHEMBL6434876 0.92 MAPT (0.50) MAPTHTTALDH1A1LMNAGAA
SCHEMBL6434868 0.92 MAPT (0.50) MAPTHTTALDH1A1LMNAGAA
SCHEMBL16135276 0.89 MAPT (0.46) MAPTHTTALDH1A1LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402651-B2 Macromolecular compounds with a core-shell structure H.C. STARCK GMBH & CO. KG (DE) 2008-07-22 US disclosed
US-20050215760-A1 Macromolecular compounds with a core-shell structure H. C. STARCK GMBH (DE) 2005-09-29 US disclosed
EP-1580217-A1 Macromolecular compounds with core-shell structure H.C. Starck GmbH (DE) 2005-09-28 EP disclosed