Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.82 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955887 | 1.00 | MAOB (0.82) | MAOBHDAC6HSD17B10CYP1A2TRPV1 | |
| SCHEMBL4909255 | 0.99 | MAOB (0.84) | MAOBHDAC6HSD17B10CYP1A2TRPV1 | |
| SCHEMBL11458668 | 0.99 | MAOB (0.84) | MAOBHDAC6HSD17B10CYP1A2TRPV1 | |
| SCHEMBL4909262 | 0.99 | MAOB (0.84) | MAOBHDAC6HSD17B10CYP1A2TRPV1 | |
| SCHEMBL11445628 | 0.99 | MAOB (0.84) | MAOBHDAC6HSD17B10CYP1A2TRPV1 | |
| SCHEMBL17340465 | 0.98 | MAOB (0.84) | MAOBHDAC6HSD17B10CYP1A2TRPV1 | |
| SCHEMBL13271652 | 0.90 | MAOB (1.00) | MAOBCYP1A2TRPV1HPGDSMN1; SMN2 | |
| SCHEMBL3831982 | 0.90 | MAOB (1.00) | MAOBCYP1A2TRPV1HPGDSMN1; SMN2 | |
| SCHEMBL3831979 | 0.90 | MAOB (1.00) | MAOBCYP1A2TRPV1HPGDSMN1; SMN2 | |
| SCHEMBL3120231 | 0.90 | MAOB (1.00) | MAOBCYP1A2TRPV1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361685-B2 | Compounds for use in the treatment of skin conditions | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-04-22 | — | — | US | claimed |