Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.30 |
| ▸ | CCKBR | P32239 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333497 | 0.82 | CYP17A1 (0.44) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL20714284 | 0.78 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL19241941 | 0.78 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL427775 | 0.78 | CYP11B1 (0.47) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL19229972 | 0.76 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL19229977 | 0.74 | CYP17A1 (0.43) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL427342 | 0.74 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL4461862 | 0.72 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL420876 | 0.72 | — | — | |
| SCHEMBL1219428 | 0.71 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435713-B2 | Compositions and methods for removal of incidental soils from fabric articles via soil modification | THE PROCTER & GAMBLE COMPANY (US) | 2008-10-14 | — | — | US | disclosed |
| EP-1451403-B1 | COMPOSITIONS AND METHODS FOR REMOVAL OF INCIDENTAL SOILS FROM FABRIC ARTICLES VIA SOIL MODIFICATION | PROCTER & GAMBLE (US) | 2006-10-04 | — | — | EP | disclosed |
| US-7105637-B2 | Dehydro-estriol (8-DHE3) and dehydro-pregnanetriol (7-DHPT), methods of their synthesis | WILLIAM MARSH RICE UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |
| US-20050137108-A1 | Compositions and methods for removal of incidental soils from fabric articles via soil modification | THE PROCTER & GAMBLE COMPANY | 2005-06-23 | — | — | US | disclosed |
| US-6890892-B2 | Compositions and methods for removal of incidental soils from fabric articles via soil modification | PROCTER & GAMBLE COMPANY (US) | 2005-05-10 | — | — | US | disclosed |
| EP-1451403-A1 | COMPOSITIONS AND METHODS FOR REMOVAL OF INCIDENTAL SOILS FROM FABRIC ARTICLES VIA SOIL MODIFICATION | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| US-20030220314-A1 | Dehydro-estriol (8-DHE3) and dehydro-pregnanetriol (7-DHPT), and methods of their synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-11-27 | — | — | US | disclosed |
| US-20030119711-A1 | Compositions and methods for removal of incidental soils from fabric articles via soil modification | PROCTOR & GAMBLE COMPANY, THE | 2003-06-26 | — | — | US | disclosed |
| WO-2003050344-A1 | COMPOSITIONS AND METHODS FOR REMOVAL OF INCIDENTAL SOILS FROM FABRIC ARTICLES VIA SOIL MODIFICATION | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220314-A1 | Dehydro-estriol (8-DHE3) and dehydro-pregnanetriol (7-DHPT), and methods of their synthesis | HSD17B3, HSD17B13, HSD17B11 | CYP19A1 79/4885CYP11B1 26/4885CYP11B2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.