Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1757334 | 0.85 | PTGDR2 (0.77) | PTGDR2PTGS1CYP2C9PTGDR | |
| SCHEMBL2208147 | 0.84 | PTGDR2 (1.00) | PTGDR2PTGS1 | |
| SCHEMBL1757750 | 0.83 | PTGDR2 (0.94) | PTGDR2CYP2C9 | |
| SCHEMBL1757438 | 0.83 | PTGDR2 (0.84) | PTGDR2PTGS1CYP2C9PTGDR | |
| SCHEMBL1757500 | 0.82 | PTGDR2 (0.73) | PTGDR2PTGS1CYP2C9PTGDR | |
| SCHEMBL2206147 | 0.82 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL1757801 | 0.81 | PTGDR2 (0.81) | PTGDR2PTGS1 | |
| SCHEMBL1757810 | 0.81 | PTGDR2 (0.95) | PTGDR2PTGS1 | |
| SCHEMBL1757445 | 0.81 | PTGDR2 (0.77) | PTGDR2PTGS1 | |
| SCHEMBL1757969 | 0.80 | PTGDR2 (0.78) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405215-B2 | Indole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof | WYETH (US) | 2008-07-29 | — | — | US | claimed |