Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 10/20 | 0.68 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.68 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.68 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.68 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.68 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.68 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4578256 | 0.95 | GRIN1 (0.62) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4418701 | 0.89 | GRIN1 (0.68) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4551013 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577504 | 0.81 | GRIN1 (0.65) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4576934 | 0.81 | GRIN2B (0.68) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL12466320 | 0.80 | MEN1 (0.62) | GRIN1GRIN2BFAAH | |
| SCHEMBL4414796 | 0.80 | GRIN1 (0.69) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577467 | 0.80 | GRIN2D (0.69) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4579394 | 0.79 | GRIN1 (0.65) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577185 | 0.79 | GRIN1 (0.68) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409477-B1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2008-09-17 | — | — | EP | disclosed |